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On August 17, 2012 when sweet little Sadie was 17 months old, she was diagnosed with Juvenile Myelomonocytic Leukemia, or JMML, a rare form of leukemia.  Sadie’s life saving plan of action is chemotherapy and a bone marrow transplant.  Two bone marrow donors were found after a few weeks of testing and searching.  This was a huge blessing!  After receiving chemo at home, she was admitted to the hospital on November 6the.  She has started a more intense chemo regiment and is scheduled for her bone marrow transplant on November 16th.

Once Sadie has had her transplant, she will be in the hospital for about 8 weeks.  During this time only one parent can stay overnight with her.  When Sadie is discharged from the hospital, the family will have to stay in the area for more than 100 days.  Doctors will need to keep close tabs on Sadie’s progress and be sure her body is accepting the marrow.  The hospital providing these procedures is 170 miles away from their home.  On top of the emotional toll this has obviously taken on Sadie and her family, they will have many mounting expenses.  Between medicals bills, lodging, food, and other expenses, the cost will add up very quickly.

Thank you for helping us raise money towards covering the expenses that are continuing to rise, so they can stay focused on Sadie and not have to worry so much about the financial aspect of this situation.  Whether you can give financially or not, you can still help by keeping Sadie and her family in your prayers!

 Update:

Here is a summary of the last few months:   As you know, Sadie received a bone marrow transplant in November and around the first of January, was able to leave the hospital and go to a nearby place so she could visit the clinic as needed…several times a week.  The chimerism test showed the donor cells at 93% with the goal being 100%.  In mid January, Sadie’s platelets and red blood cells were in normal range.  JMML is an aggressive cancer and need to be treated aggressively. 

Many visits to the clinic are needed to monitor Sadie’s progress and keep medicines in check.   They are also monitoring her liver enzymes since they are up.  In mid February, Sadie developed a rash that quickly covered her entire body.  After testing, the doctors had said she has acute GVHD (graph vs host disease) in her liver.   The treatment regiment for the GVHD in the liver will last quite a while.  She continued to have a lot of problems with high liver enzymes and returned to the hospital for a few days to get the proper balance of drugs.  Blood pressure and heart rate are being closely monitored to keep them in as normal range as possible.  Eventually, her levels have come down considerably although they still remain a little high.   By March, Sadie’s donor cells are at 100% and continue to stay there.  It is a constant process for the clinic to monitor and adjust meds as needed.  She is also cutting teeth during this time and is not allowed any meds for that.  She continues to have a good appetite and her spirits are high.   In early March, Sadie celebrated her 2nd birthday!  Yeah!  

April began fairly quiet but changed about the middle of the month.  She woke up vomiting and became dehydrated with an extremely high heart rate.  She was admitted to the hospital and moved into the pediatric intensive care unit (PICU).  Her condition was critical and they placed a breathing tube down her throat.  (It remained for 4 days.) She tested positive for Rotavirus.  They continued to work to stabilize her and were considering placing her on life support but she showed signs of improvement at the last minute.  PTL!     After about 6 days, she was released from PICU and moved into the BMTU (unit where she received bone marrow treatment previously).  She was there for about another week before she was released.  She began to regain her strength to sit up and walk again.  She continues to improve daily but will be in the Chapel Hill area for several more months.  Your prayers and support are most welcome as they journey through this!
 

 Latest Info:
I must thank everyone again for all the prayers and/or positive thoughts for Sadie's recovery. At Sadie's clinic visit this morning I learned that statistically BMT patients that enter the PICU usually do not have a good outcome, especially those that experience systemic shock. The PICU docs and Sadie's main doc have never seen anything like Sadie's recovery. Sadie's blood work shows that her counts have returned to normal levels or just slightly higher/lower than normal. Except for her magnesium level is very low. Also she tested negative for the rotavirus much quicker than anticipated. It was expected that because of Sadie's new and suppressed immune system, it would take a few weeks to a month for the virus to leave her system. She tested negative for rotavirus a week and half ago! It would also be common to develop GVHD in the gut after experiencing such trauma. So far, it does not seem as though Sadie has developed GVHD in her gut. As for the GVHD in Sadie's liver, today her liver enzymes (ALT) were 57, down from Monday's number of 89. During Sadie's stay in the PICU, because she was so sick and because so many medicines were shoveled into her tiny body, ALT shot up to around 500. A normal ALT is between 5-45.

I remain in constant praise of God. I believe He heard our prayers and showed us a miracle.




 

 

 

 

Jeff and Candace Hulsey

100 East Bank Road

Wilmington, NC  28412